The Cellular Engineering and Nano-Therapeutics Laboratory in the University of Michigan, Department of Biomedical Engineering, is seeking outstanding organic/medicinal chemists to be part of a multi-disciplinary team including materials scientists, pharmacologists, physicians, and engineers focusing on the development of novel polymer therapeutics. This postdoctoral position is available immediately for one year and subject to renewal for subsequent years based on research progress and the availability of funds.

Qualifications: The ideal candidate will have a Ph.D. in organic or medicinal chemistry; strong technical expertise in modern synthetic methods and techniques; extensive experience in multistep synthesis, purification, and characterization of organic molecules using modern chromatographic and analytical techniques including NMR, LC/MS, UV, IR, and GPC; solid knowledge of computers and experience with databases; excellent communication skills in English and ability to interact effectively with other postdoctoral fellows, graduate and undergraduate students in a fast-paced environment; excellent organization and time management skills; initiative; and ability to plan, carry out, and troubleshoot synthetic steps with minimal supervision.

Responsibilities: The primary focus of this position is the design, synthesis, and characterization of novel small molecule linkers plus sugar- and peptide-based targeting ligands to be incorporated in new polymer-drug conjugates for site-specific drug delivery. The selected candidate will work on the synthesis and purification of small organic molecules, characterization of the synthesized compounds by spectrometric techniques, and performance of related laboratory maintenance. She/He will analyze experimental data, identify synthetic, methodological, or technical problems, and adjust experimental protocols to ensure research progress towardsthe stated milestones; gather, summarize, and report all results on regular bases. She/He will participate in biweekly group meetings, communicate project progress, and interact with multiple collaborators.

Contact: Interested candidates should send a cover letter, resume, and the names and contact information (mailing address, e-mail, and phone number) of at least three professional references preferably via e-mail to:

Mohamed E.H. El-Sayed, Ph.D.
University of Michigan
Department of Biomedical Engineering
1101 Beal Ave
Lurie Biomedical Engineering, Room 2150
Ann Arbor, MI 48109-2110
E-mail:
Phone: (734) 615-9404
Web: www.bme.umich.edu/centlab.php

The University of Michigan is a premier research institute. The Department of Biomedical Engineering has one of the leading programs in the country with a stimulating, multidisciplinary, and highly collaborative research environment. The CENT LAB is housed in the newly-constructed Lurie Biomedical Engineering Building with state-of-the-art facilities and brand new research equipments.