SAIC-Frederick, Inc., a subsidiary of SAIC, is the Operations and Technical Support Contractor for the National Cancer Institute at Frederick (NCI-Frederick) a federally funded research and development center. SAIC-Frederick, Inc. is one of four related NCI contracts on-site and serves as the infrastructure support for the entire center. The contract is the largest single research contract awarded by the Department of Health and Human Services (DHHS) and it is the department's only Government-owned, contractor-operated facility contract.

SAIC-Frederick, Inc. is currently searching for a Scientist II for our Synthetic Chemistry Lab in Frederick, MD. Responsibilities will be to initiate and conduct the design, synthesis, purification, and characterization of bioactive molecules directed toward treatment of cancer; carry out cutting-edge medicinal chemistry research leading to new approaches to the design of clinical candidates. Play a significant role in the generation of lead compounds for various chemical biology programs, by utilizing multiple strategies such as HTS hit validation, lead optimization and structure-based design.

REQUIRED SKILLS: Possession of a Doctoral degree from an accredited college or university appropriate to biomedical research, or eight (8) years related experience in lieu of degree. Foreign educated candidates who have completed part or all of their education outside of the United States must have their foreign education evaluated by an SAIC-approved accrediting organization to assure that it has met the equivalency of the qualifications of degree work in the United States. In addition to education requirements, should have had two or more years of competent, innovative research experience beyond doctoral training with experience with natural product and/or multi-step synthesis of biologically complex active organic compounds in the pharmaceutical or academic environment, and at least one year of experience in project management of multiple drug development projects. Will possess a strong record of published accomplishments. Proficiency in identifying structure activity relationships (SAR), selectivity profiles, pharmacokinetics and in vitro efficacy. Extensive experience with modern analytical and purification methods, including NMR, IR, LCMS, HPLC and various forms of chromatography is required. In addition, experience in high throughput parallel synthesis and analytical chemistry is required. This position is subject to obtaining a Public Trust Clearance. Experience in applied research will be beneficial.

We offer an excellent salary and benefits program, including medical, dental, and life, 401(k) retirement savings plan, and educational assistance.

For immediate consideration and to see the full job description, please visit our website at www.saic.com and view position # 106255.

SAIC values diversity in the workplace. EEO M/F/D/V